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A young vampire joins an unlikely ally to hunt prey during the coronavirus quarantine.
Sang-hyun (Song Kang-ho), a respected priest, volunteers for an experimental procedure that may lead to a cure for a deadly virus. He gets infected and dies, but a blood transfusion of unknown origin brings him back to life as a vampire. Now, Sang-hyun is torn between faith and bloodlust, and has a newfound desire for Tae-ju (Kim Ok-vin), the wife of his childhood friend.
When most of the population of Earth is infected by a virus and transformed into flesh eaters and blood drinking creatures, a group of hunters lead by Tao and his sword chase the vampire zombies to eliminate them. Six non-infected survivors try to find the exit of an abandoned hospital crowded of the infected creatures. Meanwhile, the military is ready to bomb the whole area.